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Hsc70 抗体 (C-Term) (APC)

This 兔 多克隆 antibody specifically detects Hsc70 in FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7996491
发货至: 中国
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Quick Overview for Hsc70 抗体 (C-Term) (APC) (ABIN7996491)

抗原

See all Hsc70 (HSPA8) 抗体
Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

适用

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人, 大鼠, 小鼠

宿主

  • 129
  • 37
  • 9
  • 2

克隆类型

  • 114
  • 62
多克隆

标记

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This Hsc70 antibody is conjugated to APC

应用范围

  • 132
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  • 15
  • 10
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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Hsc70/HSPA8 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Hsc70, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

    别名

    HSPA8

    背景

    Background: HSPA8 (heat shock 70kDa protein 8) also known as HSC70, HSC71, HSP73, HSPA10, FORMERLY, LAP1 or LPS-ASSOCIATED PROTEIN 1, is a heat shock protein that in humans is encoded by the HSPA8 gene. The HSPA8 gene contains 9 exons and spans 5 kb. The deduced HSPA8 protein has 646 amino acids and a predicted molecular mass of 70,899 Da. The HSPA8 gene is mapped on 11q24.1. HSPA8 plays an important role in cells by transiently associating with nascent polypeptides to facilitate correct folding. HSP73 also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Rapid decay involves AU-rich binding protein AUF1, which complexes with heat-shock proteins HSC70 and HSP70, translation initiation factor EIF4G, and poly (A)-binding protein. In the absence of Il3, Hsc70 formed a complex with Hsp40 and Hip, and this complex, in association with Eif4g and Pabp, formed a high-stability complex with Bim mRNA that protected it from ribonucleases.

    Gene Full Name: heat shock protein family A (Hsp70) member 8

    Sequence Similarities: Belongs to the heat shock protein 70 family.

    基因ID

    3312

    UniProt

    P11142
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