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HSP70 1A 抗体 (C-Term) (APC)

The APC-conjugated 兔 多克隆 anti-HSP70 1A antibody (ABIN7996337) specifically detects HSP70 1A in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7996337
发货至: 中国
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Quick Overview for HSP70 1A 抗体 (C-Term) (APC) (ABIN7996337)

抗原

See all HSP70 1A (HSPA1A) 抗体
HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 107
  • 73
多克隆

标记

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This HSP70 1A antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Hsp70/HSPA1A/HSPA1B Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by four amino acids,from the related rat sequence by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Hsp70, different from the related mouse sequence by four amino acids and from the related rat sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

    别名

    HSPA1A

    背景

    Background: HSPA1 (heat shock 70kDa protein 1A) also known as HSP70-1, HSPA1A, HSP70-1A, HSP72 or HSP70I, is a protein that in humans is encoded by the HSPA1A gene. This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. The HSPA1A gene encodes a predicted 641-amino acid protein. The HSPA1 gene is mapped on 6p21.33. Shimizu et al. (1999) found that peripheral blood mononuclear cells of 18 major depression patients expressed a short HSPA1A transcript that utilized exon 1 rather than exon 2, which is found in the more common HSPA1A transcript. No protein was associated with expression of this short HSPA1A mRNA, possibly due to lack of a TATA box or loss of internal ribosome binding sites. Treatment with BGP-15, a pharmacologic inducer of Hsp72 that can protect against obesity-induced insulin resistance, improved muscular architecture, strength, and contractile function in severely affected diaphragm muscles in mdx dystrophic mice.

    Gene Full Name: heat shock protein family A (Hsp70) member 1A/1B

    Sequence Similarities: Belongs to the heat shock protein 70 family.

    基因ID

    3303, 3304

    UniProt

    P0DMV8

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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