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HSPB8 抗体 (AA 1-196) (Fluoro550)

The Fluoro550-conjugated 小鼠 单克隆 anti-HSPB8 antibody (Clone 7D8) (ABIN7996190) specifically detects HSPB8 in FACS. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN7996190
发货至: 中国
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Quick Overview for HSPB8 抗体 (AA 1-196) (Fluoro550) (ABIN7996190)

抗原

See all HSPB8 抗体
HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

适用

  • 122
  • 56
  • 55
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 94
  • 27
  • 1
小鼠

克隆类型

  • 78
  • 44
单克隆

标记

  • 48
  • 10
  • 7
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HSPB8 antibody is conjugated to Fluoro550

应用范围

  • 84
  • 45
  • 37
  • 35
  • 26
  • 22
  • 15
  • 13
  • 13
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

7D8
  • 抗原表位

    • 43
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-196

    原理

    Anti-HSPB8/Hsp22 Antibody (monoclonal, 7D8) Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human HSPB8,Hsp22 shares 94.4%,95.4% amino acid (aa) sequence identity with mouse,rat HSPB8,Hsp22,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human HSPB8/Hsp22 recombinant protein (Position: M1-T196). Human HSPB8/Hsp22 shares 94.4% and 95.4% amino acid (aa) sequence identity with mouse and rat HSPB8/Hsp22, respectively.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

    别名

    HSPB8

    背景

    Background: Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

    Gene Full Name: heat shock protein family B (small) member 8

    基因ID

    26353

    UniProt

    Q9UJY1
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