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Haptoglobin 抗体 (Middle Region) (Fluoro594)

This 兔 多克隆 antibody specifically detects Haptoglobin in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7996026
发货至: 中国
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Quick Overview for Haptoglobin 抗体 (Middle Region) (Fluoro594) (ABIN7996026)

抗原

See all Haptoglobin (HP) 抗体
Haptoglobin (HP)

适用

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宿主

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克隆类型

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  • 89
多克隆

标记

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This Haptoglobin antibody is conjugated to Fluoro594

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    Middle Region

    原理

    Anti-Haptoglobin/HP Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Haptoglobin.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Haptoglobin (HP)

    别名

    HP

    背景

    Background: Haptoglobin (HP), is a protein that in humans is encoded by the HP gene. Haptoglobin, a plasma glycoprotein that binds free hemoglobin, has a tetrameric structure of 2 alpha and 2 beta polypeptides that are covalently associated by disulfide bonds. Haptoglobin is homologous to serine proteases of the chymotrypsinogen family. In the chimpanzee, there are 3 genes in the haptoglobin family (haptoglobin, HP, haptoglobin-related, HPR, and haptoglobin-primate, HPP), whereas only 2 genes exist in humans (HP and HPR). There are similarities between the primary structures of the alpha chain and of light chains of gamma globulins. The alpha haptoglobin locus is on the long arm of chromosome 16, where its exact cytogenetic location is 16q22.2. A major function of haptoglobin is to bind hemoglobin (Hb) to form a stable Hp-Hb complex and thereby prevent Hb-induced oxidative tissue damage. Haptoglobin is an unusual secretory protein in that it is proteolytically processed in the endoplasmic reticulum and not in the Golgi. The human haptoglobin HP*2 allele contains a 1.7-kb intragenic duplication that arose after a unique nonhomologous recombination between the prototype HP*1 alleles.

    Gene Full Name: haptoglobin

    Sequence Similarities: Belongs to the peptidase S1 family.

    基因ID

    3240

    UniProt

    P00738

    途径

    Transition Metal Ion Homeostasis
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