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GBP1 抗体 (C-Term) (FITC)

The FITC-conjugated 兔 多克隆 anti-GBP1 antibody (ABIN7995839) specifically detects GBP1 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7995839
发货至: 中国
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Quick Overview for GBP1 抗体 (C-Term) (FITC) (ABIN7995839)

抗原

See all GBP1 抗体
GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))

适用

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宿主

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克隆类型

  • 64
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多克隆

标记

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This GBP1 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Guanylate-binding protein 1 GBP1 Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human GBP1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))

    别名

    GBP1

    背景

    Background: Interferons induce a large number of genes in their target cells, including those coding for guanylate-binding proteins (GBPs). GBPs, such as GBP1, are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. The 593-amino acid GBP1 protein shares 77 % and 88 % identity with GBP2 and GBP3, respectively. All GBPs, including GBP1, have a conserved N-terminal globular GTP-binding domain containing 2 consensus sequences and a third T (L/V)RD sequence not found in other GTPases. The GBP1 gene to the GBP gene cluster on chromosome 1p22.2. It is located telomeric to GBP2 and centromeric to GBP3. High expression of GBP1, GBP2, and GBP3 are in endothelial cells after stimulation with IFNG, TNF, or IL1B .

    Gene Full Name: guanylate binding protein 1

    Sequence Similarities: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.

    基因ID

    2633

    UniProt

    P32455

    途径

    Cellular Response to Molecule of Bacterial Origin
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