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GAMT 抗体 (AA 1-236) (Cy3)

The 兔 多克隆 anti-GAMT antibody is suitable to detect GAMT in samples from 人, 大鼠 和 小鼠. It has been validated for FACS.
产品编号 ABIN7995637
发货至: 中国
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Quick Overview for GAMT 抗体 (AA 1-236) (Cy3) (ABIN7995637)

抗原

See all GAMT 抗体
GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GAMT antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-236

    原理

    Anti-GAMT Antibody Cy3 Conjugated

    预测反应

    Human GAMT shares 88.1%,86.8% amino acid (aa) sequence identity with mouse,rat GAMT.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GAMT recombinant protein (Position: M1-G236). Human GAMT shares 88.1% and 86.8% amino acid (aa) sequence identity with mouse and rat GAMT.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

    别名

    GAMT

    背景

    Background: Guanidinoacetate N-methyltransferase (EC 2.1.1.2) is an enzyme that catalyzes the chemical reaction and is encoded by gene GAMT located on chromosome 19p13.3. The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

    Gene Full Name: guanidinoacetate N-methyltransferase

    基因ID

    2593

    UniProt

    Q14353
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