GAMT 抗体 (AA 1-236) (Cy3)
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北京 101111
Quick Overview for GAMT 抗体 (AA 1-236) (Cy3) (ABIN7995637)
抗原
See all GAMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-236
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原理
- Anti-GAMT Antibody Cy3 Conjugated
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预测反应
- Human GAMT shares 88.1%,86.8% amino acid (aa) sequence identity with mouse,rat GAMT.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GAMT recombinant protein (Position: M1-G236). Human GAMT shares 88.1% and 86.8% amino acid (aa) sequence identity with mouse and rat GAMT.
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
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别名
- GAMT
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背景
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Background: Guanidinoacetate N-methyltransferase (EC 2.1.1.2) is an enzyme that catalyzes the chemical reaction and is encoded by gene GAMT located on chromosome 19p13.3. The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.
Gene Full Name: guanidinoacetate N-methyltransferase
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基因ID
- 2593
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UniProt
- Q14353
抗原
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