TREML2 抗体 (AA 65-150)
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北京 101111
Quick Overview for TREML2 抗体 (AA 65-150) (ABIN749888)
抗原
See all TREML2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-150
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TREML2
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亚型
- IgG
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anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 188-237) antibody
TREML2 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 19-268) antibodyTREML2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 101-150) antibodyTREML2 适用: 人, 犬, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (N-Term) antibodyTREML2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (Middle Region) antibodyTREML2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (N-Term) antibodyTREML2 适用: 人, 犬, Pig, 兔, Cow, 马, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
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别名
- TREML2
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背景
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Synonyms: C6orf76, Chromosome 6 open reading frame 76, FLJ13693, MGC149715, MGC149716, TLT 2, TLT2, TREM like transcript 2, Trem like transcript 2 protein, Triggering receptor expressed on myeloid cells like 2, Triggering receptor expressed on myeloid cells like protein 2, TRML2_HUMAN.
Background: TREML2 is expressed throughout B cell development in addition to being expressed on macrophages and neutrophils and is the only TREM molecule to be found on lymphocytes. TREML2 is expressed on B lineage cells early in development, and the highest level of expression is detected on those mature peripheral B cell subpopulations that are involved in the initial humoral immune response against bacterial pathogens. TREML2 is unique in that it lacks either the conserved transmembrane lysine residue or ITAM/ITIMs within its own cytoplasmic domain. Thus, TREML2 does not exhibit any of the features associated with classical tyrosine-based signaling. Monocytes in the bone marrow or peripheral blood do not express detectable levels of TREML2, but its expression is up-regulated in conjunction with differentiation into macrophages. TREML2 is present on neutrophils in the bone marrow as well as the periphery, and inflammatory stimuli result in a dramatic increase in the expression of TREML2 on these cells in vivo.TREML2 is a single-pass type I membrane protein, and it contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 and TREM2, but it has distinct structural and functional properties.
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基因ID
- 79865
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UniProt
- Q5T2D2
抗原
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