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GDF15 抗体 (AA 51-199) (HRP)

This 兔 多克隆 antibody specifically detects GDF15 in WB, IHC 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7995312
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GDF15 抗体 (AA 51-199) (HRP) (ABIN7995312)

抗原

See all GDF15 抗体
GDF15 (Growth Differentiation Factor 15 (GDF15))

适用

  • 131
  • 62
  • 47
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 136
  • 18
  • 4
  • 3
  • 1

克隆类型

  • 133
  • 25
  • 2
多克隆

标记

  • 79
  • 20
  • 12
  • 7
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GDF15 antibody is conjugated to HRP

应用范围

  • 108
  • 66
  • 56
  • 41
  • 13
  • 13
  • 13
  • 10
  • 8
  • 8
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 16
    • 15
    • 13
    • 13
    • 11
    • 10
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-199

    原理

    Anti-PDF Antibody HRP Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human PDF shares 82.4% amino acid (aa) sequence identity with mouse PDF.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PDF recombinant protein (Position: H51-Q199). Human PDF shares 82.4% amino acid (aa) sequence identity with mouse PDF.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    别名

    PDF

    背景

    Background: Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.

    Gene Full Name: peptide deformylase, mitochondrial

    基因ID

    64146

    UniProt

    Q9HBH1

    途径

    SARS-CoV-2 Protein Interactome
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