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GDF15 抗体 (AA 51-199) (Cy3)

The 兔 多克隆 anti-GDF15 antibody is suitable to detect GDF15 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7995307
发货至: 中国
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北京 101111
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Quick Overview for GDF15 抗体 (AA 51-199) (Cy3) (ABIN7995307)

抗原

See all GDF15 抗体
GDF15 (Growth Differentiation Factor 15 (GDF15))

适用

  • 131
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人, 小鼠, 大鼠

宿主

  • 136
  • 18
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克隆类型

  • 133
  • 25
  • 2
多克隆

标记

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This GDF15 antibody is conjugated to Cy3

应用范围

  • 109
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Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 15
    • 13
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    AA 51-199

    原理

    Anti-PDF Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human PDF shares 82.4% amino acid (aa) sequence identity with mouse PDF.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PDF recombinant protein (Position: H51-Q199). Human PDF shares 82.4% amino acid (aa) sequence identity with mouse PDF.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    别名

    PDF

    背景

    Background: Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.

    Gene Full Name: peptide deformylase, mitochondrial

    基因ID

    64146

    UniProt

    Q9HBH1

    途径

    SARS-CoV-2 Protein Interactome
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