Grancalcin 抗体 (AA 42-217)
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北京 101111
Quick Overview for Grancalcin 抗体 (AA 42-217) (ABIN7995019)
抗原
See all Grancalcin (GCA) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 42-217
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原理
- Anti-Grancalcin/GCA Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Grancalcin/GCA Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Grancalcin/GCA recombinant protein (Position: A42-I217).
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL Immunocytochemistry/Immunofluorescence, 5 μg/mL Flow Cytometry(Fixed), 1-3 μg/1x106 cells ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
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别名
- GCA
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背景
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Background: Grancalcin is a protein that in humans is encoded by the GCA gene. This gene is mapped to 2q24.2. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction, with magnesium alone, it partitions with the granule fraction, and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
Gene Full Name: grancalcin
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分子量
- 25 kDa
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基因ID
- 25801
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UniProt
- P28676
抗原
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