Grancalcin 抗体 (AA 42-217) (Fluoro594)
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北京 101111
Quick Overview for Grancalcin 抗体 (AA 42-217) (Fluoro594) (ABIN7995013)
抗原
See all Grancalcin (GCA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 42-217
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原理
- Anti-Grancalcin/GCA Antibody Fluoro594 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Grancalcin/GCA recombinant protein (Position: A42-I217).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Grancalcin (GCA) (Grancalcin, EF-Hand Calcium Binding Protein (GCA))
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别名
- GCA
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背景
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Background: Grancalcin is a protein that in humans is encoded by the GCA gene. This gene is mapped to 2q24.2. This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction, with magnesium alone, it partitions with the granule fraction, and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.
Gene Full Name: grancalcin
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基因ID
- 25801
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UniProt
- P28676
抗原
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