GSTM2 抗体 (Middle Region) (Fluoro488)
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北京 101111
Quick Overview for GSTM2 抗体 (Middle Region) (Fluoro488) (ABIN7994340)
抗原
See all GSTM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-GSTM2 Antibody Fluoro488 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human GSTM2 shares 95.5% amino acid (aa) sequence identity with rat GSTM2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse GSTM2. Human GSTM2 shares 95.5% amino acid (aa) sequence identity with rat GSTM2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))
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别名
- GSTM2
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背景
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Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
Gene Full Name: glutathione S-transferase, mu 2
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基因ID
- 14863
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UniProt
- P15626
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途径
- Negative Regulation of Transporter Activity
抗原
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