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GSTM1 抗体 (Middle Region) (APC)

The 小鼠 单克隆 anti-GSTM1 antibody is suitable to detect GSTM1 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7994323
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GSTM1 抗体 (Middle Region) (APC) (ABIN7994323)

抗原

See all GSTM1 抗体
GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

适用

  • 80
  • 58
  • 38
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 74
  • 31
  • 1
小鼠

克隆类型

  • 72
  • 33
单克隆

标记

  • 52
  • 15
  • 10
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This GSTM1 antibody is conjugated to APC

应用范围

  • 77
  • 49
  • 31
  • 28
  • 17
  • 12
  • 10
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
Flow Cytometry (FACS)

克隆位点

11F2
  • 抗原表位

    • 23
    • 17
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-GSTM1 Antibody (monoclonal, 11F2) APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human GSTM1, which shares 70.6% and 73.5% amino acid (aa) sequence identity with mouse and rat GSTM1, respectively.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

    别名

    GSTM1

    背景

    Background: Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S-transferase. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

    Gene Full Name: glutathione S-transferase mu 1

    基因ID

    2944

    UniProt

    P09488

    途径

    Negative Regulation of Transporter Activity
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