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CRLF2 抗体 (PE)

This anti-CRLF2 antibody is a 兔 多克隆 antibody detecting CRLF2 in IF (p). Suitable for 人.
产品编号 ABIN749748
发货至: 中国

Quick Overview for CRLF2 抗体 (PE) (ABIN749748)

抗原

See all CRLF2 抗体
CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

适用

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宿主

  • 49
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克隆类型

  • 52
  • 13
多克隆

标记

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  • 1
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This CRLF2 antibody is conjugated to PE

应用范围

  • 38
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Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 特异性

    Excitation / Emission Wavelengths: 565nm/578nm

    纯化方法

    purified by Protein A

    免疫原

    KLH conjugated synthetic peptide derived from human CRLF2

    亚型

    IgG
  • 说明

    Excitation / Emission wavelength: 496nm / 578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 µg/µL

    缓冲液

    Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 4 °C for 12 months

    有效期

    12 months
  • 抗原

    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

    别名

    CRLF2

    背景

    TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.

    分子量

    41kDa

    基因ID

    64109
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