GPX3 抗体 (C-Term) (Fluoro488)
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北京 101111
Quick Overview for GPX3 抗体 (C-Term) (Fluoro488) (ABIN7994175)
抗原
See all GPX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-GPX3 Antibody Fluoro488 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human GPX3 shares 100% amino acid (aa) sequence identity with both mouse,rat GPX3.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human GPX3. Human GPX3 shares 100% amino acid (aa) sequence identity with both mouse and rat GPX3.
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亚型
- IgG
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anti-Glutathione Peroxidase 3 (Plasma) (GPX3) (AA 21-72) antibody
GPX3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 3 (Plasma) (GPX3) (AA 3-72) antibodyGPX3 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 3 (Plasma) (GPX3) (Internal Region) antibodyVerified GPX3 适用: 小鼠, 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Glutathione Peroxidase 3 (Plasma) (GPX3) (AA 93-123) antibodyGPX3 适用: 小鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal RB18898 unconjugated
anti-Glutathione Peroxidase 3 (Plasma) (GPX3) antibodyGPX3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 3 (Plasma) (GPX3) (N-Term) antibodyGPX3 适用: 小鼠, 人, 大鼠, 犬, Pig, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))
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别名
- GPX3
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背景
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Background: The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is secreted, and is abundantly found in plasma. Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies, including thyroid cancer, hepatocellular carcinoma and chronic myeloid leukemia. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
Gene Full Name: glutathione peroxidase 3
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基因ID
- 2878
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UniProt
- P22352
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途径
- Thyroid Hormone Synthesis
抗原
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