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Glutathione Peroxidase 1 抗体 (Middle Region) (HRP)

This 小鼠 单克隆 antibody specifically detects Glutathione Peroxidase 1 in WB, IHC 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7994157
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Glutathione Peroxidase 1 抗体 (Middle Region) (HRP) (ABIN7994157)

抗原

See all Glutathione Peroxidase 1 (GPX1) 抗体
Glutathione Peroxidase 1 (GPX1)

适用

  • 115
  • 79
  • 77
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 95
  • 20
  • 4
  • 2
小鼠

克隆类型

  • 73
  • 48
单克隆

标记

  • 49
  • 10
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
This Glutathione Peroxidase 1 antibody is conjugated to HRP

应用范围

  • 73
  • 53
  • 44
  • 40
  • 36
  • 29
  • 16
  • 11
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

8B10
  • 抗原表位

    • 23
    • 13
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-GPX1 Antibody (monoclonal, 8B10) HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by six amino acids,from the related rat sequence by five amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human GPX1, different from the related mouse sequence by six amino acids and from the related rat sequence by five amino acids.

    亚型

    IgG2b
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Glutathione Peroxidase 1 (GPX1)

    别名

    GPX1

    背景

    Background: Glutathione peroxidase 1, also known as, GPX-1 is an enzyme that in humans is encoded by the GPX1 gene. It is mapped to 3p21.31. This gene encodes a member of the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. It has been reported that the protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. GPX1 is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA.

    Gene Full Name: glutathione peroxidase 1

    基因ID

    2876

    UniProt

    P07203

    途径

    Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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