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GRIA4 抗体 (AA 176-350)

The 兔 多克隆 anti-GRIA4 antibody is suitable to detect GRIA4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 FACS.
产品编号 ABIN7993729
发货至: 中国
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Quick Overview for GRIA4 抗体 (AA 176-350) (ABIN7993729)

抗原

See all GRIA4 抗体
GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

适用

  • 81
  • 67
  • 44
  • 2
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  • 2
人, 小鼠, 大鼠

宿主

  • 83
  • 2

克隆类型

  • 73
  • 12
多克隆

标记

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  • 2
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  • 1
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This GRIA4 antibody is un-conjugated

应用范围

  • 65
  • 28
  • 27
  • 19
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  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB), Flow Cytometry (FACS)

质量等级

Carrier-free
  • 抗原表位

    • 15
    • 11
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
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    • 1
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    • 1
    AA 176-350

    原理

    Anti-Ionotropic Glutamate receptor 4/GRIA4 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human GRIA4 shares 99% amino acid (aa) sequence identity with both mouse,rat GRIA4.

    产品特性

    Anti-Ionotropic Glutamate receptor 4/GRIA4 Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GRIA4 recombinant protein (Position: Q176-K350). Human GRIA4 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA4.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

    别名

    GRIA4

    背景

    Background: Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate (AMPA). Some haplotypes of this gene show a positive association with schizophrenia. What's more, glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels.

    Gene Full Name: glutamate ionotropic receptor AMPA type subunit 4

    分子量

    101 kDa

    基因ID

    2893

    UniProt

    P48058

    途径

    PI3K-Akt Signaling
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