GRIA2 抗体 (AA 25-360)
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北京 101111
Quick Overview for GRIA2 抗体 (AA 25-360) (ABIN7993696)
抗原
See all GRIA2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 25-360
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原理
- Anti-Ionotropic Glutamate receptor 2/GRIA2 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human GRIA2 shares 99% amino acid (aa) sequence identity with both mouse,rat GRIA2.
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产品特性
- Anti-Ionotropic Glutamate receptor 2/GRIA2 Antibody. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRIA2 recombinant protein (Position: N25-I360). Human GRIA2 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA2.
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody
GRIA2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7G6 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 35-175) antibodyGRIA2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7A7A3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 413-527) antibodyGRIA2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 175-430) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 25-360) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (Extracellular), (N-Term) antibodyKO Validated GRIA2 适用: 大鼠 WB, IHC, IP, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (Extracellular), (N-Term) antibodyGRIA2 适用: 大鼠 WB, IF, IC, LCI 宿主: 豚鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (N-Term) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (C-Term) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (C-Term) antibodyGRIA2 适用: 大鼠 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S21-32 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat Immunocytochemistry, 0.5-1 μg/mL, Human Immunofluorescence, 2 μg/mL, Mouse Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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别名
- GRIA2
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背景
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Background: Glutamate receptor 2, also known as GLUR2, is a protein that in humans is encoded by the GRIA2 gene. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. GLUR2's cytogenetic location is 4q32.1. The crystal structures of the GLUR2 ligand-binding core in the apo state and in the presence of the antagonist DNQX, the partial agonist kainate, and the full agonists AMPA and glutamate.GLUR2 plays a major role in depression at synapses in which glutamate remains in the synaptic cleft for prolonged periods of time during normal operation of the synapse. The overexpression of GLUR2 increases dendritic spine size and density in hippocampal neurons, and more remarkably, induces spine formation in GABA-releasing interneurons that normally lack spines.
Gene Full Name: glutamate ionotropic receptor AMPA type subunit 2
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分子量
- 110 kDa
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基因ID
- 14800
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UniProt
- P42262
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途径
- PI3K-Akt Signaling
抗原
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