电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

GAD 抗体 (AA 14-122) (Fluoro647)

This 兔 多克隆 antibody specifically detects GAD in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7993596
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GAD 抗体 (AA 14-122) (Fluoro647) (ABIN7993596)

抗原

See all GAD (GAD1) 抗体
GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

适用

  • 165
  • 96
  • 91
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 123
  • 48
  • 3
  • 2

克隆类型

  • 110
  • 66
多克隆

标记

  • 75
  • 15
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GAD antibody is conjugated to Fluoro647

应用范围

  • 114
  • 58
  • 36
  • 35
  • 20
  • 19
  • 15
  • 13
  • 13
  • 13
  • 11
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 28
    • 19
    • 17
    • 15
    • 11
    • 10
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 14-122

    原理

    Anti-GAD67/GAD1 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human GAD67 shares 95% amino acid (aa) sequence identity with both mouse,rat GAD67.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GAD67 recombinant protein (Position: N14-D122). Human GAD67 shares 95% amino acid (aa) sequence identity with both mouse and rat GAD67.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

    别名

    GAD1

    背景

    Background: Glutamate decarboxylase 1 (brain, 67 kDa) (GAD67), also known as GAD1, is a human gene. It is mapped to 2q31.1. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

    Gene Full Name: glutamate decarboxylase 1

    Sequence Similarities: Belongs to the group II decarboxylase family.

    基因ID

    2571

    UniProt

    Q99259
You are here: