Glucose-6-Phosphate Dehydrogenase 抗体 (AA 315-515) (Fluoro594)
Our Local Distributor
北京 101111
Quick Overview for Glucose-6-Phosphate Dehydrogenase 抗体 (AA 315-515) (Fluoro594) (ABIN7993459)
抗原
See all Glucose-6-Phosphate Dehydrogenase (G6PD) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 315-515
-
原理
- Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Fluoro594 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- Human G6PD shares 95%,96% amino acid (aa) sequences identity with mouse,rat G6PD,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- Glucose-6-Phosphate Dehydrogenase (G6PD)
-
别名
- G6PD
-
背景
-
Background: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.
Gene Full Name: glucose-6-phosphate dehydrogenase
Sequence Similarities: Belongs to the glucose-6-phosphate dehydrogenase family.
-
基因ID
- 2539
-
UniProt
- P11413
-
途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
-