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GCKR 抗体 (AA 8-569) (Biotin)

The 兔 多克隆 anti-GCKR antibody is suitable to detect GCKR in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7993411
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GCKR 抗体 (AA 8-569) (Biotin) (ABIN7993411)

抗原

See all GCKR 抗体
GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

适用

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人, 大鼠, 小鼠

宿主

  • 74
  • 5
  • 1

克隆类型

  • 75
  • 5
多克隆

标记

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  • 1
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This GCKR antibody is conjugated to Biotin

应用范围

  • 53
  • 17
  • 14
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  • 7
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
    • 12
    • 5
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    • 3
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    • 1
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    AA 8-569

    原理

    Anti-GCKR Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GCKR recombinant protein (Position: Q8-Q569).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

    别名

    GCKR

    背景

    Background: The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells). This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

    Gene Full Name: glucokinase regulator

    基因ID

    2646

    UniProt

    Q14397

    途径

    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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