Gephyrin 抗体 (AA 148-736)
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北京 101111
Quick Overview for Gephyrin 抗体 (AA 148-736) (ABIN7993113)
抗原
See all Gephyrin (GPHN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 148-736
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原理
- Anti-Gephyrin/GPHN Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Gephyrin/GPHN Antibody. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Gephyrin/GPHN recombinant protein (Position: K148-L736).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- Gephyrin (GPHN)
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别名
- GPHN
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背景
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Background: Gephyrin is a protein that in humans is encoded by the GPHN gene. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.
Gene Full Name: gephyrin
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分子量
- 93 kDa
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基因ID
- 10243
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UniProt
- Q9NQX3
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途径
- Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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