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Geminin 抗体 (AA 21-196) (PE)

The PE-conjugated 兔 多克隆 anti-Geminin antibody (ABIN7993067) specifically detects Geminin in FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7993067
发货至: 中国
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Quick Overview for Geminin 抗体 (AA 21-196) (PE) (ABIN7993067)

抗原

See all Geminin (GMNN) 抗体
Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

适用

  • 98
  • 23
  • 12
人, 小鼠

宿主

  • 71
  • 30

克隆类型

  • 53
  • 48
多克隆

标记

  • 52
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Geminin antibody is conjugated to PE

应用范围

  • 47
  • 42
  • 42
  • 26
  • 21
  • 21
  • 15
  • 10
  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-196

    原理

    Anti-Geminin/GMNN Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Geminin/GMNN recombinant protein (Position: V21-E196).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

    别名

    GMNN

    背景

    Background: Geminin, DNA replication inhibitor, also known as GMNN, is a protein in humans encoded by the GMNN gene. This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.

    Gene Full Name: geminin DNA replication inhibitor

    基因ID

    51053

    UniProt

    O75496

    途径

    EGFR Signaling Pathway, DNA Replication
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