Geminin 抗体 (AA 21-196) (Biotin)
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北京 101111
Quick Overview for Geminin 抗体 (AA 21-196) (Biotin) (ABIN7993059)
抗原
See all Geminin (GMNN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-196
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原理
- Anti-Geminin/GMNN Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Geminin/GMNN recombinant protein (Position: V21-E196).
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亚型
- IgG
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anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 110-209) antibody
GMNN 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 21-196) antibodyGMNN 适用: 人, 小鼠 WB, IHC, IF, ELISA, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 1-206) antibodyGMNN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) antibodyGMNN 适用: 人 IHC, IF 宿主: 小鼠 Monoclonal CPTC-GMNN-1 unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 110-142) antibodyGMNN 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 110-209) antibodyGMNN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 96-123) antibodyGMNN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB20074 unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 1-209) antibodyGMNN 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Geminin, DNA Replication Inhibitor (GMNN) antibodyKD Validated GMNN 适用: 人 WB 宿主: 兔 Monoclonal 25GB3475 unconjugated Recombinant Antibody
anti-Geminin, DNA Replication Inhibitor (GMNN) (AA 5-209) antibodyGMNN 适用: 人 IHC, IHC (p) 宿主: 小鼠 Monoclonal EM6 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
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别名
- GMNN
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背景
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Background: Geminin, DNA replication inhibitor, also known as GMNN, is a protein in humans encoded by the GMNN gene. This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
Gene Full Name: geminin DNA replication inhibitor
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基因ID
- 51053
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UniProt
- O75496
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途径
- EGFR Signaling Pathway, DNA Replication
抗原
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