GIP 抗体 (AA 44-85)
Our Local Distributor
北京 101111
Quick Overview for GIP 抗体 (AA 44-85) (ABIN7992871)
抗原
See all GIP 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 44-85
-
原理
- Anti-GIP Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- coli-derived mouse GIP recombinant protein (Position: Y44-Q85). Mouse GIP shares 92.9% amino acid (aa) sequence identity with both human,rat GIP.
-
产品特性
- Anti-GIP Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived mouse GIP recombinant protein (Position: Y44-Q85). Mouse GIP shares 92.9% amino acid (aa) sequence identity with both human and rat GIP.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- GIP (Gastric Inhibitory Polypeptide (GIP))
-
别名
- Gip
-
背景
-
Background: Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide, is an inhibiting hormone of the secretin family of hormones. GIP is thought to have significant effects on fatty acid metabolism through stimulation of lipoprotein lipase activity in adipocytes. Additionally, GIP release has been demonstrated in the ruminant animal and may play a role in nutrient partitioning in milk production (lipid metabolism). Recently, GIP appeared as a major player in bone remodelling. It was evidenced that genetic ablation of the GIP receptor in mice resulted in profound alterations of bone microarchitecture through modification of the adipokine network. Furthermore, the deficiency in GIP receptors has also been associated in mice with a dramatic decrease in bone quality and a subsequent increase in fracture risk.
Gene Full Name: gastric inhibitory polypeptide
-
分子量
- 18 kDa
-
基因ID
- 14607
-
UniProt
- P48756
-
途径
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
抗原
-