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FH 抗体 (N-Term) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-FH antibody (ABIN7991945) specifically detects FH in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7991945
发货至: 中国
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Quick Overview for FH 抗体 (N-Term) (Biotin) (ABIN7991945)

抗原

See all FH 抗体
FH (Fumarate Hydratase (FH))

适用

  • 130
  • 56
  • 54
  • 13
  • 6
  • 1
人, 小鼠, 大鼠

宿主

  • 93
  • 41
  • 3

克隆类型

  • 86
  • 51
多克隆

标记

  • 65
  • 12
  • 8
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FH antibody is conjugated to Biotin

应用范围

  • 86
  • 46
  • 43
  • 33
  • 30
  • 14
  • 13
  • 12
  • 11
  • 8
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 26
    • 15
    • 9
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-FH Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human FH, which shares 100% and 97.8% amino acid (aa) sequence identity with mouse and rat FH, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    FH (Fumarate Hydratase (FH))

    别名

    FH

    背景

    Background: Fumarase (or fumaratehydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety. This enzyme participates in 2 metabolic pathways: citric acid cycle, reductive citric acid cycle (CO2 fixation), and is also important in renal cell carcinoma. Mutations in this gene have been associated with the development of leiomyomas in the skin and uterus in combination with renal cell carcinoma.

    Gene Full Name: fumarate hydratase

    基因ID

    2271

    UniProt

    P07954
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