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FOXM1 抗体 (AA 48-763) (Cy3)

This 兔 多克隆 antibody specifically detects FOXM1 in FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7991481
发货至: 中国
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Quick Overview for FOXM1 抗体 (AA 48-763) (Cy3) (ABIN7991481)

抗原

See all FOXM1 抗体
FOXM1 (Forkhead Box M1 (FOXM1))

适用

  • 88
  • 49
  • 47
  • 4
  • 3
  • 2
  • 2
  • 2
人, 大鼠, 小鼠

宿主

  • 77
  • 13

克隆类型

  • 74
  • 16
多克隆

标记

  • 41
  • 7
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This FOXM1 antibody is conjugated to Cy3

应用范围

  • 39
  • 32
  • 28
  • 19
  • 11
  • 7
  • 6
  • 4
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 13
    • 12
    • 12
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 48-763

    原理

    Anti-FOXM1 Antibody Cy3 Conjugated

    预测反应

    Human FOXM1 shares 78.9%,81.1% amino acid (aa) sequence identity with mouse,rat FOXM1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FOXM1 recombinant protein (Position: K48-Q763). Human FOXM1 shares 78.9% and 81.1% amino acid (aa) sequence identity with mouse and rat FOXM1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    FOXM1 (Forkhead Box M1 (FOXM1))

    别名

    FOXM1

    背景

    Background: Forkhead box protein M1, also called FOXM1, is a protein that in humans is encoded by the FOXM1 gene. It is mapped to 12p13.33. The protein encoded by this gene is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. FOXM1 gene is now known as a human proto-oncogene. Abnormal upregulation of FOXM1 is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It was hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. What's more, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of FOXM1 brain washes normal cells to adopt cancer-like epigenome.

    Gene Full Name: forkhead box M1

    基因ID

    2305

    UniProt

    Q08050

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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