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SIRPA 抗体 (AA 151-250)

This anti-SIRPA antibody is a 兔 多克隆 antibody detecting SIRPA in WB, FACS 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN749453
发货至: 中国

Quick Overview for SIRPA 抗体 (AA 151-250) (ABIN749453)

抗原

See all SIRPA 抗体
SIRPA (Signal-Regulatory Protein alpha (SIRPA))

适用

  • 82
  • 40
  • 36
  • 10
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  • 3
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  • 3
人, 小鼠

宿主

  • 67
  • 39
  • 1
  • 1
  • 1

克隆类型

  • 60
  • 48
  • 1
多克隆

标记

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  • 10
  • 5
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
This SIRPA antibody is un-conjugated

应用范围

  • 68
  • 52
  • 28
  • 24
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  • 17
  • 14
  • 11
  • 10
  • 3
  • 1
  • 1
  • 1
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Western Blotting (WB), Flow Cytometry (FACS), ELISA
  • 抗原表位

    • 15
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CD172a

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    SIRPA (Signal-Regulatory Protein alpha (SIRPA))

    别名

    Sirp alpha

    背景

    Synonyms: BIT, MFR, P84, SIRP, MYD-1, SHPS1, CD172A, PTPNS1, Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, Signal-regulatory protein alpha-2, Sirp-alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-3, SIRPA, MYD1

    Background: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.

    基因ID

    140885

    UniProt

    P78324
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