FIP1L1 抗体 (AA 23-558)
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北京 101111
Quick Overview for FIP1L1 抗体 (AA 23-558) (ABIN7990918)
抗原
See all FIP1L1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 23-558
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原理
- Anti-FIP1L1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FIP1L1 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FIP1L1 recombinant protein (Position: E23-E558).
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亚型
- IgG
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anti-FIP1 Like 1 (FIP1L1) antibody
FIP1L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) (AA 1-300) antibodyFIP1L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) (AA 23-558) antibodyFIP1L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) (AA 1-378) antibodyFIP1L1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H4 unconjugated
anti-FIP1 Like 1 (FIP1L1) (AA 509-558) antibodyFIP1L1 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, Pig, 豚鼠, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) antibodyFIP1L1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-FIP1 Like 1 (FIP1L1) antibodyFIP1L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- FIP1L1 (FIP1 Like 1 (FIP1L1))
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别名
- FIP1L1
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背景
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Background: Factor interacting with PAPOLA and CPSF1 (i.e, FIP1L1, also termed Pre-mRNA 3'-end-processing factor FIP1) is a protein that in humans is encoded by the FIP1L1 gene (also known as Rhe, FIP1, and hFip1). This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity. Its N-terminus contains a PAP-binding site and its C-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of human genes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. This gene fusion and chromosomal deletion is the cause of some forms of idiopathic hypereosinophilic syndrome (HES). This syndrome, recently reclassified as chronic eosinophilic leukemia (CEL), is responsive to treatment with tyrosine kinase inhibitors. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Full Name: factor interacting with PAPOLA and CPSF1
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分子量
- 72 kDa
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基因ID
- 81608
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UniProt
- Q6UN15
抗原
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