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Fibrillarin 抗体 (AA 77-138) (Cy3)

The Cy3-conjugated 兔 多克隆 anti-Fibrillarin antibody (ABIN7990280) specifically detects Fibrillarin in FACS. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN7990280
发货至: 中国
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Quick Overview for Fibrillarin 抗体 (AA 77-138) (Cy3) (ABIN7990280)

抗原

See all Fibrillarin (FBL) 抗体
Fibrillarin (FBL)

适用

  • 74
  • 40
  • 40
  • 13
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 猴

宿主

  • 67
  • 10
  • 1

克隆类型

  • 54
  • 24
多克隆

标记

  • 39
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Fibrillarin antibody is conjugated to Cy3

应用范围

  • 62
  • 25
  • 23
  • 21
  • 18
  • 18
  • 16
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 77-138

    原理

    Anti-Fibrillarin/FBL Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Fibrillarin/FBL recombinant protein (Position: K77-N138).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Fibrillarin (FBL)

    别名

    FBL

    背景

    Background: rRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the FBL gene. This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

    Gene Full Name: fibrillarin rRNA 2'-O-methyltransferase

    基因ID

    2091

    UniProt

    P22087

    途径

    Ribonucleoside Biosynthetic Process
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