Fatty Acid Synthase 抗体 (AA 1-226)
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Quick Overview for Fatty Acid Synthase 抗体 (AA 1-226) (ABIN7990035)
抗原
See all Fatty Acid Synthase (FASN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 1-226
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原理
- Anti-Fatty Acid Synthase/FASN Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3%,90.7% amino acid (aa) sequence identity with mouse,rat FASN,respectively.
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产品特性
- Anti-Fatty Acid Synthase/FASN Antibody. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3% and 90.7% amino acid (aa) sequence identity with mouse and rat FASN, respectively.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL Immunocytochemistry/Immunofluorescence, 5 μg/mL Immunofluorescence, 5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Fatty Acid Synthase (FASN)
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别名
- FASN
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背景
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Background: Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. It is mapped to 17q25. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Gene Full Name: fatty acid synthase
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分子量
- 273 kDa
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基因ID
- 2194
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UniProt
- P49327
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途径
- AMPK Signaling
抗原
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