FOXRED2 抗体 (AA 44-623)
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北京 101111
Quick Overview for FOXRED2 抗体 (AA 44-623) (ABIN7989540)
抗原
See all FOXRED2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 44-623
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原理
- Anti-FOXRED2 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-FOXRED2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))
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别名
- FOXRED2
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背景
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Background: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.
Gene Full Name: FAD dependent oxidoreductase domain containing 2
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分子量
- 80 kDa
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基因ID
- 80020
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UniProt
- Q8IWF2
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途径
- SARS-CoV-2 Protein Interactome
抗原
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