FOXRED2 抗体 (AA 44-623) (Cy3)
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北京 101111
Quick Overview for FOXRED2 抗体 (AA 44-623) (Cy3) (ABIN7989531)
抗原
See all FOXRED2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 44-623
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原理
- Anti-FOXRED2 Antibody Cy3 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623).
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))
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别名
- FOXRED2
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背景
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Background: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.
Gene Full Name: FAD dependent oxidoreductase domain containing 2
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基因ID
- 80020
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UniProt
- Q8IWF2
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途径
- SARS-CoV-2 Protein Interactome
抗原
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