DIS3 抗体 (AA 43-878) (Fluoro594)
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北京 101111
Quick Overview for DIS3 抗体 (AA 43-878) (Fluoro594) (ABIN7989324)
抗原
See all DIS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 43-878
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原理
- Anti-DIS3 Antibody Fluoro594 Conjugated
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预测反应
- Human DIS3 shares 92.8% amino acid (aa) sequence identity with mouse DIS3.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DIS3 recombinant protein (Position: H43-K878). Human DIS3 shares 92.8% amino acid (aa) sequence identity with mouse DIS3.
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亚型
- IgG
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anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 1-958) antibody
DIS3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 861-956) antibodyDIS3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 861-956) antibodyDIS3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 295-323) antibodyDIS3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24091 unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) antibodyDIS3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB8525 unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 295-323) antibodyDIS3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 30-187) antibodyDIS3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 290-339) antibodyDIS3 适用: 人, 大鼠, 小鼠, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 302-331), (Middle Region) antibodyDIS3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
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别名
- DIS3
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背景
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Background: Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. The DIS3 gene encodes a catalytic subunit of the exosome complex, an essential RNA degradation machinery involved in multiple aspects of RNA metabolism, including RNA processing, quality control, and turnover. DIS3 functions as an exonuclease, playing a key role in degrading various RNA species, such as messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA). Its activity is crucial for maintaining cellular RNA homeostasis and gene expression regulation. Dysregulation of DIS3 expression or activity has been linked to various human diseases, including cancer and neurodegenerative disorders. Understanding the molecular mechanisms underlying DIS3 function is essential for elucidating its role in RNA metabolism and its potential implications for disease pathology and therapeutic targeting.
Gene Full Name: DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
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基因ID
- 22894
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UniProt
- Q9Y2L1
抗原
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