EIF6 抗体 (AA 66-210) (Fluoro647)
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Quick Overview for EIF6 抗体 (AA 66-210) (Fluoro647) (ABIN7989142)
抗原
See all EIF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 66-210
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原理
- Anti-integrin beta 4 binding protein/EIF6 Antibody Fluoro647 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human EIF6 shares 99.3% amino acid (aa) sequence identity with both mouse,rat EIF6.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EIF6 recombinant protein (Position: N66-T210). Human EIF6 shares 99.3% amino acid (aa) sequence identity with both mouse and rat EIF6.
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 66-210) antibody
EIF6 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 66-210) antibodyEIF6 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 小鼠 Monoclonal 2I11 unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) antibodyEIF6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 1-245) antibodyEIF6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 1-245) antibodyEIF6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (AA 146-245) antibodyEIF6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (C-Term) antibodyEIF6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (Middle Region) antibodyEIF6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (C-Term) antibodyEIF6 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 绵羊, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 6 (EIF6) (N-Term) antibodyEIF6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
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别名
- EIF6
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背景
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Background: EIF6 (Eukaryotic Translation Initiation Factor 6), also called EIF3A or ITGB4BP, is a human gene. By fluorescence in situ hybridization, Sanvito et al. (1998) mapped the ITGB4BP gene to 20q11.2. Ceci et al. (2003) demonstrated that the ribosomal 60S subunit is activated by release of EIF6. In the cytoplasm, EIF6 is bound to free 60S but not to 80S subunits. Furthermore, EIF6 interacts in the cytoplasm with RACK1, a receptor for activated protein kinase C. Gandin et al. (2008) demonstrated that mammalian eIF6 is required for efficient initiation of translation in vivo. Eif6-null mouse embryos were lethal at preimplantation. Heterozygous mice had 50 % reduction of eIF6 levels in all tissues, and showed reduced mass of hepatic and adipose tissues due to a lower number of cells and to impaired G1/S cell cycle progression.
Gene Full Name: eukaryotic translation initiation factor 6
Sequence Similarities: Belongs to the WD repeat ESC family.
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基因ID
- 3692
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UniProt
- P56537
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途径
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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