Plexin A1 抗体 (PE)
Quick Overview for Plexin A1 抗体 (PE) (ABIN749223)
抗原
See all Plexin A1 (PLXNA1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Plexin A1
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亚型
- IgG
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anti-Plexin A1 (PLXNA1) (AA 1100-1200) antibody
PLXNA1 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8A10A6 unconjugated
anti-Plexin A1 (PLXNA1) (AA 1100-1200) antibodyPLXNA1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7B8H9 unconjugated
anti-Plexin A1 (PLXNA1) antibodyPLXNA1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 43-300) antibodyPLXNA1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 623-636), (Extracellular) antibodyPLXNA1 适用: 人 WB, IHC, FACS, LCI, IF 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 901-1000) antibodyPLXNA1 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 32-296) antibodyPLXNA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Plexin A1 (PLXNA1) (AA 623-636), (Extracellular) antibody (FITC)PLXNA1 适用: 人 FACS, LCI 宿主: 兔 Polyclonal FITC
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应用备注
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FCM: 1:20-100
Optimal working dilution should be determined by the investigator. -
说明
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Exitation/Emission: 480,565nm/578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4 °C
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有效期
- 12 months
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- Plexin A1 (PLXNA1)
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别名
- Plexin A1
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背景
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Plexins are a family of large integral membrane proteins that complex with neuropilins to form semaphorin co-receptors. The extracellular region of plexins contain a semaphorin domain, multiple glycine rich motifs, and MET related sequences. The cytoplasmic region contains a Sex/Plexin domain and putative tyrosine phosphorylation sites that mediate signal transduction after activation. This region in Plexin A1 binds the RhoGTPases, Rnd1 and RhoD. Recruitment of Rnd1 has been implicated in the cytoskeletal collapse that occurs after semaphorin mediated activation of Plexin A1, while RhoD may block this collapsing activity through interaction with the cytoplasmic region of Plexin A1. The expression of Plexin A1, along with the co receptor Neuropilin 1, is upregulated in neurons after central nervous system injury. The axons from these neurons cannot cross semaphorin 3A containing regions at the site of injury. Thus, semaphorin 3A and its co-receptors, Plexin A1 and Neuropilin 1, may have significant roles in axon regeneration after neuronal injury.
Subcellular location: Extracellular
Synonyms: NOV, NOV/plexin A1 protein, NOVP, Plexin1, PlexinA1, PLXN1, PLXNA1, PLXNA1, protein, Semaphorin receptor NOV, PLXA1_HUMAN. -
基因ID
- 5361
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途径
- Smooth Muscle Cell Migration
抗原
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