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ERG 抗体 (AA 20-274) (Fluoro647)

This 兔 多克隆 antibody specifically detects ERG in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7988367
发货至: 中国
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Quick Overview for ERG 抗体 (AA 20-274) (Fluoro647) (ABIN7988367)

抗原

See all ERG 抗体
ERG (ERG, ETS transcription factor (ERG))

适用

  • 103
  • 59
  • 56
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  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
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  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 80
  • 22
  • 1

克隆类型

  • 52
  • 51
多克隆

标记

  • 62
  • 7
  • 5
  • 3
  • 3
  • 3
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  • 3
  • 3
  • 3
  • 1
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  • 1
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This ERG antibody is conjugated to Fluoro647

应用范围

  • 51
  • 40
  • 27
  • 26
  • 18
  • 15
  • 9
  • 9
  • 9
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-274

    原理

    Anti-ERG Antibody Fluoro647 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ERG recombinant protein (Position: E20-Q274).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ERG (ERG, ETS transcription factor (ERG))

    别名

    ERG

    背景

    Background: ERG (ETS-related gene) is an oncogene. ERG is a member of the ETS (erythroblast transformation-specific) family of transcription factors. The ERG gene encodes for a protein, also called ERG, that functions as a transcriptional regulator. This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined.

    Gene Full Name: ETS transcription factor ERG

    基因ID

    2078

    UniProt

    P11308
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