EDC4 抗体 (AA 1082-1388) (Fluoro550)
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北京 101111
Quick Overview for EDC4 抗体 (AA 1082-1388) (Fluoro550) (ABIN7987778)
抗原
See all EDC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1082-1388
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原理
- Anti-EDC4 Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EDC4 recombinant protein (Position: K1082-L1388).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
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别名
- EDC4
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背景
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Background: Enhancer of mRNA-decapping protein 4 is a protein that in humans is encoded by the EDC4 gene. Enhancer of mRNA decapping 4 (EDC4) was originally identified as the autoantigen Ge-1 from a Sjgren's syndrome patient later diagnosed with primary biliary cirrhosis. EDC4 (also known as HEDLS) was later identified as an essential component of cytoplasmic P-bodies responsible for mRNA decapping and degradation. Identified EDC4 protein is found as a pair of isoforms generated by alternative splicing and contains several WD domains and a putative nuclear localization signal. EDC4 co-localizes with other P-body decapping proteins such as DCP1A, DCP2 and GW182. Experimental evidence suggests that EDC4 may be involved in miRNA-mediated translation repression.
Gene Full Name: enhancer of mRNA decapping 4
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基因ID
- 23644
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UniProt
- Q6P2E9
抗原
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