SH3G2 抗体 (AA 65-292) (Fluoro647)
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Quick Overview for SH3G2 抗体 (AA 65-292) (Fluoro647) (ABIN7987596)
抗原
See all SH3G2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 65-292
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原理
- Anti-SH3GL2 Antibody (monoclonal, 6I8E1) Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SH3GL2 recombinant protein (Position: R65-Q292).
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亚型
- IgG2a
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SH3G2 (Endophilin-A1 (SH3G2))
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别名
- SH3GL2
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背景
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Background: Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene. Endophilin proteins are part of a large family of Bin/Amphiphysin/Rvs (BAR) domain proteins that are involved in cell membrane remodeling. The endophilins are encoded by five genes, which produce endophilin A 1-3 and B 1-2. Endophilins are involved in many cellular mechanisms, such as synaptic vesicle recycling, receptor trafficking, and membrane remodeling processes. Research studies indicate that endophilin 1 (endophilin A1, SH3GL2) can induce different membrane shapes and participate in the morphogenesis of dendritic spines. Endophilin 1 is also involved in regulating blood brain barrier permeability via the EGFR-JNK pathway.
Gene Full Name: SH3 domain containing GRB2 like 2, endophilin A1
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基因ID
- 6456
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UniProt
- Q99962
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途径
- Neurotrophin Signaling Pathway, EGFR Downregulation
抗原
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