EFS 抗体 (AA 183-553) (Biotin)
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北京 101111
Quick Overview for EFS 抗体 (AA 183-553) (Biotin) (ABIN7987421)
抗原
See all EFS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 183-553
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原理
- Anti-EFS Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human EFS shares 82.2% amino acid (aa) sequence identity with mouse EFS.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EFS recombinant protein (Position: E183-T553). Human EFS shares 82.2% amino acid (aa) sequence identity with mouse EFS.
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亚型
- IgG
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anti-Embryonal Fyn-Associated Substrate (EFS) (AA 367-399) antibody
EFS 适用: 人 WB 宿主: 兔 Polyclonal RB54269 unconjugated
anti-Embryonal Fyn-Associated Substrate (EFS) (AA 1-468) antibodyEFS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- EFS (Embryonal Fyn-Associated Substrate (EFS))
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别名
- EFS
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背景
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Background: The protein encoded by this gene is a member of the CAS (CRK-associated substrate) family of adaptor proteins which typically serve as scaffolds for the assembly of larger signaling complexes. These complexes form at the cell surface where integrin binding leads to the subsequent phosphorylation of a CAS protein. Additional binding of SRC family kinases leads to CAS hyperphosphorylation and the creation of binding sites for CRK and other proteins that cause actin cytoskeleton reorganization. This gene plays a role in integrin-mediated cell attachment, spreading, and migration and also plays a role in both normal and malignant cellular transformation. This broadly expressed gene has been shown to play a role in neurite outgrowth and its expression in the thymus and lymphocytes is important for T cell maturation and the development of immunological self-tolerance. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Gene Full Name: embryonal Fyn-associated substrate
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基因ID
- 10278
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UniProt
- O43281
抗原
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