NSMCE2 抗体 (AA 14-228) (Fluoro647)
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北京 101111
Quick Overview for NSMCE2 抗体 (AA 14-228) (Fluoro647) (ABIN7986919)
抗原
See all NSMCE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-228
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原理
- Anti-NSMCE2 Antibody Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NSMCE2 recombinant protein (Position: F14-D228).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
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别名
- NSMCE2
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背景
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Background: This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.
Gene Full Name: NSE2 SUMO ligase component of SMC5/6 complex
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基因ID
- 286053
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UniProt
- Q96MF7
抗原
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