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E2F5 抗体 (AA 121-346) (PE)

The 兔 多克隆 anti-E2F5 antibody is suitable to detect E2F5 in samples from 人. It has been validated for FACS.
产品编号 ABIN7986907
发货至: 中国
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Quick Overview for E2F5 抗体 (AA 121-346) (PE) (ABIN7986907)

抗原

See all E2F5 抗体
E2F5

适用

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宿主

  • 45
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克隆类型

  • 45
  • 4
多克隆

标记

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This E2F5 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 12
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    AA 121-346

    原理

    Anti-E2F5 Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human E2F5 recombinant protein (Position: C121-Y346).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    E2F5

    别名

    E2F5

    背景

    Background: Transcription factor E2F5 is a protein that in humans is encoded by the E2F5 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.

    Gene Full Name: E2F transcription factor 5

    基因ID

    1875

    UniProt

    Q15329
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