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E2F4 抗体 (N-Term) (APC)

This 兔 多克隆 antibody specifically detects E2F4 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7986807
发货至: 中国
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Quick Overview for E2F4 抗体 (N-Term) (APC) (ABIN7986807)

抗原

See all E2F4 抗体
E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))

适用

  • 96
  • 41
  • 33
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 87
  • 9
  • 2

克隆类型

  • 62
  • 36
多克隆

标记

  • 64
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This E2F4 antibody is conjugated to APC

应用范围

  • 53
  • 41
  • 30
  • 28
  • 17
  • 16
  • 11
  • 9
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 18
    • 12
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-E2F4 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human E2F4, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))

    别名

    E2F4

    背景

    Background: Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. This gene is mapped to 16q22.1. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. Additionally, it plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.

    Gene Full Name: E2F transcription factor 4

    基因ID

    1874

    UniProt

    Q16254

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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