DUSP2 抗体 (AA 1-250)
Our Local Distributor
北京 101111
Quick Overview for DUSP2 抗体 (AA 1-250) (ABIN7986465)
抗原
See all DUSP2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 1-250
-
原理
- Anti-DUSP2 Antibody
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.
-
产品特性
- Anti-DUSP2 Antibody. Tested in WB, IHC, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human DUSP2 recombinant protein (Position: M1-G250). Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))
-
别名
- DUSP2
-
背景
-
Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.
Gene Full Name: dual specificity phosphatase 2
-
分子量
- 34 kDa
-
基因ID
- 1844
-
UniProt
- Q05923
抗原
-