DUSP2 抗体 (AA 1-250) (APC)
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Quick Overview for DUSP2 抗体 (AA 1-250) (APC) (ABIN7986462)
抗原
See all DUSP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-250
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原理
- Anti-DUSP2 Antibody APC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DUSP2 recombinant protein (Position: M1-G250). Human DUSP2 shares 85.6% amino acid (aa) sequence identity with mouse DUSP2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))
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别名
- DUSP2
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背景
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Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.
Gene Full Name: dual specificity phosphatase 2
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基因ID
- 1844
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UniProt
- Q05923
抗原
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