Doublecortin 抗体 (N-Term) (HRP)
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北京 101111
Quick Overview for Doublecortin 抗体 (N-Term) (HRP) (ABIN7986290)
抗原
See all Doublecortin (DCX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Doublecortin/DCX Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Doublecortin.
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亚型
- IgG
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anti-Doublecortin (DCX) (AA 362-411) antibody
DCX 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2G5 unconjugated
anti-Doublecortin (DCX) (AA 232-242) antibodyVerified DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 69-81) antibodyVerified DCX 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 1-360) antibodyDCX 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Doublecortin (DCX) (AA 200-250) antibodyDCX 适用: 人, 小鼠 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR168J unconjugated Recombinant Antibody
anti-Doublecortin (DCX) (AA 362-411) antibodyDCX 适用: 人 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Doublecortin (DCX) (AA 108-360) antibodyDCX 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 11-360) antibodyDCX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (pSer335) antibodyDCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 107-137) antibodyDCX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15193 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Doublecortin (DCX)
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别名
- DCX
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背景
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Background: Neuronal migration protein doublecortin, also known as doublin or lissencephalin-X, is a protein that in humans is encoded by the DCX gene. This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia (double cortex syndrome) in females and lissencephaly (smooth brain syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: doublecortin
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基因ID
- 1641
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UniProt
- O43602
抗原
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