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Dopamine Receptor d1 抗体 (Middle Region) (HRP)

The 兔 多克隆 anti-Dopamine Receptor d1 antibody is suitable to detect Dopamine Receptor d1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7986235
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Dopamine Receptor d1 抗体 (Middle Region) (HRP) (ABIN7986235)

抗原

See all Dopamine Receptor d1 (DRD1) 抗体
Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

适用

  • 91
  • 73
  • 52
  • 9
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 100
  • 4
  • 1

克隆类型

  • 92
  • 12
多克隆

标记

  • 39
  • 9
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This Dopamine Receptor d1 antibody is conjugated to HRP

应用范围

  • 66
  • 36
  • 30
  • 27
  • 26
  • 25
  • 18
  • 17
  • 14
  • 9
  • 8
  • 8
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 16
    • 16
    • 16
    • 11
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-Dopamine Receptor D1/DRD1 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human DRD1, different from the related rat and mouse sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

    别名

    DRD1

    背景

    Background: Dopamine receptor D1, also known as DRD1, is a human gene. It is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins. D2 receptors inhibit adenylyl cyclase, but D1 receptors stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. Dopamine D1 and D2 receptors are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1 receptors regulate neuron growth and differentiation, influence behaviour and modify dopamine D2 receptor-mediated events. And the presence of a D1 receptor gene restriction fragment length polymorphism will be helpful for future disease linkage studies. DRD1 also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.

    Gene Full Name: dopamine receptor D1

    基因ID

    1812

    UniProt

    P21728

    途径

    cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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