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DBH 抗体 (AA 40-545) (Fluoro488)

The 兔 多克隆 anti-DBH antibody is suitable to detect DBH in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7986220
发货至: 中国
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Quick Overview for DBH 抗体 (AA 40-545) (Fluoro488) (ABIN7986220)

抗原

See all DBH 抗体
DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

适用

  • 87
  • 22
  • 21
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 67
  • 13
  • 9
  • 1

克隆类型

  • 66
  • 24
多克隆

标记

  • 59
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DBH antibody is conjugated to Fluoro488

应用范围

  • 64
  • 41
  • 27
  • 15
  • 11
  • 8
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 10
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-545

    原理

    Anti-Dopamine beta Hydroxylase/DBH Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Dopamine beta Hydroxylase/DBH recombinant protein (Position: S40-N545).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

    别名

    DBH

    背景

    Background: Dopamine beta-hydroxylase  (DBH), also known as dopamine beta-monooxygenase, is an enzyme  (EC1.14.17.1) that in humans is encoded by the DBH gene. Dopamine beta-hydroxylase catalyzes the chemical reaction. It is mapped to 9q34.2. The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders.

    Gene Full Name: dopamine beta-hydroxylase

    基因ID

    1621

    UniProt

    P09172

    途径

    Carbohydrate Homeostasis
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