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DOK7 抗体 (Middle Region) (PE)

The 兔 多克隆 anti-DOK7 antibody is suitable to detect DOK7 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7986169
发货至: 中国
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Quick Overview for DOK7 抗体 (Middle Region) (PE) (ABIN7986169)

抗原

See all DOK7 抗体
DOK7 (Docking Protein 7 (DOK7))

适用

人, 小鼠, 大鼠

宿主

  • 58
  • 4
  • 1

克隆类型

  • 59
  • 4
多克隆

标记

  • 23
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DOK7 antibody is conjugated to PE

应用范围

  • 45
  • 22
  • 15
  • 13
  • 13
  • 13
  • 8
  • 7
  • 5
  • 3
  • 2
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 11
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-DOK7 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human DOK7, which shares 86.2% amino acid (aa) sequence identity with mouse DOK7.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DOK7 (Docking Protein 7 (DOK7))

    别名

    DOK7

    背景

    Background: Dok-7 is a non-catalytic cytoplasmic adaptor protein that is expressed specifically in muscle and is essential for the formation of neuromuscular synapses. Further, Dok-7 contains pleckstrin homology (PH) and phosphotyrosine-binding (PTB) domains that are critical for Dok-7 function. It is mapped to 4p16.3. The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

    Gene Full Name: docking protein 7

    基因ID

    285489

    UniProt

    Q18PE1

    途径

    Skeletal Muscle Fiber Development
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