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DDIT3 抗体 (AA 17-168) (Cy3)

The Cy3-conjugated 兔 多克隆 anti-DDIT3 antibody (ABIN7986029) specifically detects DDIT3 in FACS. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN7986029
发货至: 中国
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Quick Overview for DDIT3 抗体 (AA 17-168) (Cy3) (ABIN7986029)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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小鼠, 大鼠

宿主

  • 167
  • 14

克隆类型

  • 136
  • 45
多克隆

标记

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This DDIT3 antibody is conjugated to Cy3

应用范围

  • 141
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  • 17
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  • 14
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Flow Cytometry (FACS)
  • 抗原表位

    • 22
    • 16
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    • 12
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    • 7
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    • 1
    • 1
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    • 1
    • 1
    AA 17-168

    原理

    Anti-Ddit3 Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Ddit3 recombinant protein (Position: E17-A168).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    Ddit3

    背景

    Background: DNA damage-inducible transcript 3, also known as C/EBP homologous protein (CHOP), is a pro-apoptotictranscription factor that is encoded by the DDIT3 gene. It is mapped to 12q13.3. This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

    Gene Full Name: DNA-damage inducible transcript 3

    基因ID

    13198

    UniProt

    P35639

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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